Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis

The aim of the study was to investigate the influence of allelic imbalance (AI) in several loci of tumor suppressor genes in 3p region on the non-small cell lung cancer (NSCLC) development. We evaluated the frequency of loss of heterozygosity and/or microsatellite imbalance (LOH/MSI) and assessed th...

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Detalles Bibliográficos
Autores principales: Antczak, Adam, Migdalska-Sęk, Monika, Pastuszak-Lewandoska, Dorota, Czarnecka, Karolina, Nawrot, Ewa, Domańska, Daria, Kordiak, Jacek, Górski, Paweł, Brzeziańska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667378/
https://www.ncbi.nlm.nih.gov/pubmed/23504373
http://dx.doi.org/10.1007/s12032-013-0532-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667378/
https://www.ncbi.nlm.nih.gov/pubmed/23504373
http://dx.doi.org/10.1007/s12032-013-0532-9

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