Cargando…

Significant frequency of allelic imbalance in 3p region covering RARβ and MLH1 loci seems to be essential in molecular non-small cell lung cancer diagnosis

The aim of the study was to investigate the influence of allelic imbalance (AI) in several loci of tumor suppressor genes in 3p region on the non-small cell lung cancer (NSCLC) development. We evaluated the frequency of loss of heterozygosity and/or microsatellite imbalance (LOH/MSI) and assessed th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antczak, Adam, Migdalska-Sęk, Monika, Pastuszak-Lewandoska, Dorota, Czarnecka, Karolina, Nawrot, Ewa, Domańska, Daria, Kordiak, Jacek, Górski, Paweł, Brzeziańska, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667378/ https://www.ncbi.nlm.nih.gov/pubmed/23504373 http://dx.doi.org/10.1007/s12032-013-0532-9

Ejemplares similares

Allelic imbalance in 1p, 7q, 9p, 11p, 12q and 16q regions in non-small cell lung carcinoma and its clinical association: a pilot study
por: Czarnecka, Karolina H., et al.
Publicado: (2013)

CTLA-4 Expression and Polymorphisms in Lung Tissue of Patients with Diagnosed Non-Small-Cell Lung Cancer
por: Antczak, Adam, et al.
Publicado: (2013)

Expression of STAT5, COX-2 and PIAS3 in Correlation with NSCLC Histhopathological Features
por: Pastuszak-Lewandoska, Dorota, et al.
Publicado: (2014)

Quantitative analysis of mRNA expression levels and DNA methylation profiles of three neighboring genes: FUS1, NPRL2/G21 and RASSF1A in non-small cell lung cancer patients
por: Pastuszak-Lewandoska, Dorota, et al.
Publicado: (2015)

The Expression Levels of IL-4/IL-13/STAT6 Signaling Pathway Genes and SOCS3 Could Help to Differentiate the Histopathological Subtypes of Non-Small Cell Lung Carcinoma
por: Pastuszak-Lewandoska, Dorota, et al.
Publicado: (2018)

Diagnostic value of DNA alteration: loss of heterozygosity or allelic imbalance—promising for molecular staging of prostate cancers
por: Bryś, Magdalena, et al.
Publicado: (2013)

Altered miRNA expression in pulmonary sarcoidosis
por: Kiszałkiewicz, Justyna, et al.
Publicado: (2016)

Serum Extracellular Vesicle-Derived miRNAs in Patients with Non-Small Cell Lung Cancer—Search for Non-Invasive Diagnostic Biomarkers
por: Kryczka, Jolanta, et al.
Publicado: (2021)

Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients
por: Piotrowski, Wojciech J., et al.
Publicado: (2015)

Clinicopathological Significance of Overall Frequency of Allelic Loss (OFAL) in Lesions Derived from Thyroid Follicular Cell
por: Migdalska-Sęk, Monika, et al.
Publicado: (2019)

Diagnostic value of PPARδ and miRNA-17 expression levels in patients with non-small cell lung cancer
por: Migdalska-Sęk, Monika, et al.
Publicado: (2021)

Respiratory Tract Oncobiome in Lung Carcinogenesis: Where Are We Now?
por: Czarnecka-Chrebelska, Karolina H., et al.
Publicado: (2023)

Expression of inflammatory interleukins and selected miRNAs in non-small cell lung cancer
por: Dutkowska, Agata, et al.
Publicado: (2021)

A Strong Decrease in TIMP3 Expression Mediated by the Presence of miR-17 and 20a Enables Extracellular Matrix Remodeling in the NSCLC Lesion Surroundings
por: Czarnecka, Karolina H., et al.
Publicado: (2019)

CTLA-4 gene polymorphisms and their influence on predisposition to autoimmune thyroid diseases (Graves’ disease and Hashimoto's thyroiditis)
por: Pastuszak-Lewandoska, Dorota, et al.
Publicado: (2012)

Evaluation of selected IL6/STAT3 pathway molecules and miRNA expression in chronic obstructive pulmonary disease
por: Kiszałkiewicz, J. M., et al.
Publicado: (2021)

Expression analysis of selected classes of circulating exosomal miRNAs in soccer players as an indicator of adaptation to physical activity
por: Domańska-Senderowska, Daria, et al.
Publicado: (2017)

Role of Beta-Carotene in Lung Cancer Primary Chemoprevention: A Systematic Review with Meta-Analysis and Meta-Regression
por: Kordiak, Jacek, et al.
Publicado: (2022)

The Significance of the Alter miR let-7a and miR-335 Expression Level Regulating the CCR7/CCL19 Axis as Potential Biomarkers of Tumor Progression in NSCLC
por: Baran, Kamila, et al.
Publicado: (2022)

Circulating miRNAs Related to Epithelial–Mesenchymal Transitions (EMT) as the New Molecular Markers in Endometriosis
por: Zubrzycka, Anna, et al.
Publicado: (2021)

The Expression of TGF-β1, SMAD3, ILK and miRNA-21 in the Ectopic and Eutopic Endometrium of Women with Endometriosis
por: Zubrzycka, Anna, et al.
Publicado: (2023)

Assessment of BMP7, SMAD4, and CDH1 Expression Profile and Regulatory miRNA-542-3p in Eutopic and Ectopic Endometrium of Women with Endometriosis
por: Zubrzycka, Anna, et al.
Publicado: (2023)

An Analysis of IL-10, IL-17A, IL-17RA, IL-23A and IL-23R Expression and Their Correlation with Clinical Course in Patients with Psoriasis
por: Kutwin, Magdalena, et al.
Publicado: (2021)

Type of training has a significant influence on the GH/IGF-1 axis but not on regulating miRNAs
por: Khalid, Katarzyna, et al.
Publicado: (2020)

Assessment of Wnt pathway selected gene expression levels in peripheral blood mononuclear cells (PBMCs) of postmenopausal patients with low bone mass
por: Stuss, Michal, et al.
Publicado: (2021)

Correlation between the Positive Effect of Vitamin D Supplementation and Physical Performance in Young Male Soccer Players
por: Brzeziański, Michał, et al.
Publicado: (2022)

Effect of physical training on parathyroid hormone and bone turnover marker profile in relation to vitamin D supplementation in soccer players
por: Brzeziański, Michał, et al.
Publicado: (2021)

Helicobacter Pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – a Pilot Study
por: Dzikowiec, Magdalena, et al.
Publicado: (2022)

Relationships between the Expression of the ACTN3 Gene and Explosive Power of Soccer Players
por: Domańska-Senderowska, Daria, et al.
Publicado: (2019)

Panel of miR-150 and linc00673, regulators of CCR6/CCL20 may serve as non-invasive diagnostic marker of non-small cell lung cancer
por: Baran, Kamila, et al.
Publicado: (2023)

Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis
por: Bosch, Almudena, et al.
Publicado: (2012)

Lynch Syndrome Associated with Two MLH1 Promoter Variants and Allelic Imbalance of MLH1 Expression
por: Hesson, Luke B, et al.
Publicado: (2015)

The significance of epigenetic alterations in lung carcinogenesis
por: Brzeziańska, Ewa, et al.
Publicado: (2012)

Nitrofuran Derivatives Cross-Resistance Evidence—Uropathogenic Escherichia coli Nitrofurantoin and Furazidin In Vitro Susceptibility Testing
por: Bielec, Filip, et al.
Publicado: (2023)

Exhaled IL-8 in Systemic Lupus Erythematosus with and without Pulmonary Fibrosis
por: Nielepkowicz-Goździńska, Agnieszka, et al.
Publicado: (2014)

Carbapenem-Resistant Gram-Negative Fermenting and Non-Fermenting Rods Isolated from Hospital Patients in Poland—What Are They Susceptible to?
por: Brauncajs, Małgorzata, et al.
Publicado: (2022)

Analysis of Cumulative Antibiogram Reports in Search for Optimal Empirical Urinary Tract Infection Treatment at the Central Teaching Hospital of the Medical University of Lodz, Poland: Results of a 3-Year Surveillance
por: Bielec, Filip, et al.
Publicado: (2023)

In Vitro Activity of Eravacycline against Carbapenemase-Producing Gram-Negative Bacilli Clinical Isolates in Central Poland
por: Brauncajs, Małgorzata, et al.
Publicado: (2023)

Analysis of The PPARD Gene Expression Level Changes in Football Players in Response To the Training Cycle
por: Domańska-Senderowska, D, et al.
Publicado: (2018)

The Comparison of Serum Exosome Protein Profile in Diagnosis of NSCLC Patients
por: Baran, Kamila, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8mfhhff4cv6ivbsgvav4nfm3u4