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Protective effect on normal brain tissue during a combinational therapy of 2-deoxy-d-glucose and hypofractionated irradiation in malignant gliomas

PURPOSE: To investigate the effect of 2-deoxy–D-glucose (2-DG), an inhibitor of glucose transport and glycolysis, on glioblastoma and the normal brain tissue during combined treatment with hypofractionated radiotherapy. MATERIALS AND METHODS: Twenty patients with malignant gliomas (18 Glioblastoma M...

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Detalles Bibliográficos
Autores principales: Venkataramanaa, Neelam K., Venkatesh, P. K., Dwarakanath, B. S., Vani, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667464/
https://www.ncbi.nlm.nih.gov/pubmed/23741257
http://dx.doi.org/10.4103/1793-5482.110274