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Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA–mRNA interactions

MicroRNAs (miRNAs) are small, noncoding RNAs involved in posttranscriptional regulation of protein-coding genes in various biological processes. In our preliminary miRNA microarray analysis, miR-375 was identified as the most underexpressed in human oral tumor versus controls. The purpose of the pre...

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Detalles Bibliográficos
Autores principales: Jung, Hyun Min, Patel, Rushi S., Phillips, Brittany L., Wang, Hai, Cohen, Donald M., Reinhold, William C., Chang, Lung-Ji, Yang, Li-Jun, Chan, Edward K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667718/
https://www.ncbi.nlm.nih.gov/pubmed/23552692
http://dx.doi.org/10.1091/mbc.E12-12-0891