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Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes

Macrophages and dendritic cells continuously survey their environment in search of foreign particles and soluble antigens. Such surveillance involves the ongoing extension of actin-rich protrusions and the consequent formation of phagosomes and macropinosomes. The signals inducing this constitutive...

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Detalles Bibliográficos
Autores principales: Bohdanowicz, Michal, Schlam, Daniel, Hermansson, Martin, Rizzuti, David, Fairn, Gregory D., Ueyama, Takehiko, Somerharju, Pentti, Du, Guangwei, Grinstein, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667723/
https://www.ncbi.nlm.nih.gov/pubmed/23576545
http://dx.doi.org/10.1091/mbc.E12-11-0789