Cargando…
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes
Macrophages and dendritic cells continuously survey their environment in search of foreign particles and soluble antigens. Such surveillance involves the ongoing extension of actin-rich protrusions and the consequent formation of phagosomes and macropinosomes. The signals inducing this constitutive...
Autores principales: | Bohdanowicz, Michal, Schlam, Daniel, Hermansson, Martin, Rizzuti, David, Fairn, Gregory D., Ueyama, Takehiko, Somerharju, Pentti, Du, Guangwei, Grinstein, Sergio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667723/ https://www.ncbi.nlm.nih.gov/pubmed/23576545 http://dx.doi.org/10.1091/mbc.E12-11-0789 |
Ejemplares similares
-
Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages
por: Canton, Johnathan, et al.
Publicado: (2016) -
Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration
por: Gu, Zhizhan, et al.
Publicado: (2011) -
Regulation of circular dorsal ruffles, macropinocytosis, and cell migration by RhoG and its exchange factor, Trio
por: Valdivia, Alejandra, et al.
Publicado: (2017) -
Hypothesis: Chemical activity regulates and coordinates the processes maintaining glycerophospholipid homeostasis in mammalian cells
por: Somerharju, Pentti, et al.
Publicado: (2020) -
CR3 ruffles FcγR’s claim over phagocytic cups
por: Frautschy, S.A.
Publicado: (2021)