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Strong Purifying Selection at Synonymous Sites in D. melanogaster
Synonymous sites are generally assumed to be subject to weak selective constraint. For this reason, they are often neglected as a possible source of important functional variation. We use site frequency spectra from deep population sequencing data to show that, contrary to this expectation, 22% of f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667748/ https://www.ncbi.nlm.nih.gov/pubmed/23737754 http://dx.doi.org/10.1371/journal.pgen.1003527 |