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Biases in the Experimental Annotations of Protein Function and Their Effect on Our Understanding of Protein Function Space

The ongoing functional annotation of proteins relies upon the work of curators to capture experimental findings from scientific literature and apply them to protein sequence and structure data. However, with the increasing use of high-throughput experimental assays, a small number of experimental st...

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Detalles Bibliográficos
Autores principales: Schnoes, Alexandra M., Ream, David C., Thorman, Alexander W., Babbitt, Patricia C., Friedberg, Iddo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667760/
https://www.ncbi.nlm.nih.gov/pubmed/23737737
http://dx.doi.org/10.1371/journal.pcbi.1003063