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Production of Cloned Pigs with Targeted Attenuation of Gene Expression

The objective of this study was to demonstrate that RNA interference (RNAi) and somatic cell nuclear transfer (SCNT) technologies can be used to attenuate the expression of specific genes in tissues of swine, a large animal species. Apolipoprotein E (apoE), a secreted glycoprotein known for its majo...

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Detalles Bibliográficos
Autores principales: Bordignon, Vilceu, El-Beirouthi, Nayla, Gasperin, Bernardo G., Albornoz, Marcelo S., Martinez-Diaz, Mario A., Schneider, Carine, Laurin, Denyse, Zadworny, David, Agellon, Luis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667777/
https://www.ncbi.nlm.nih.gov/pubmed/23737990
http://dx.doi.org/10.1371/journal.pone.0064613