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Production of Cloned Pigs with Targeted Attenuation of Gene Expression
The objective of this study was to demonstrate that RNA interference (RNAi) and somatic cell nuclear transfer (SCNT) technologies can be used to attenuate the expression of specific genes in tissues of swine, a large animal species. Apolipoprotein E (apoE), a secreted glycoprotein known for its majo...
Autores principales: | Bordignon, Vilceu, El-Beirouthi, Nayla, Gasperin, Bernardo G., Albornoz, Marcelo S., Martinez-Diaz, Mario A., Schneider, Carine, Laurin, Denyse, Zadworny, David, Agellon, Luis B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667777/ https://www.ncbi.nlm.nih.gov/pubmed/23737990 http://dx.doi.org/10.1371/journal.pone.0064613 |
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