Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia

Focal degradation of extracellular matrix (ECM) is the first step in the invasion of cancer cells. MT1-MMP is a potent membrane proteinase employed by aggressive cancer cells. In our previous study, we reported that MT1-MMP was preferentially located at membrane protrusions called invadopodia, where...

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Detalles Bibliográficos
Autores principales: Watanabe, Ayako, Hosino, Daisuke, Koshikawa, Naohiko, Seiki, Motoharu, Suzuki, Takashi, Ichikawa, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667784/
https://www.ncbi.nlm.nih.gov/pubmed/23737743
http://dx.doi.org/10.1371/journal.pcbi.1003086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667784/
https://www.ncbi.nlm.nih.gov/pubmed/23737743
http://dx.doi.org/10.1371/journal.pcbi.1003086

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