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Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia
Focal degradation of extracellular matrix (ECM) is the first step in the invasion of cancer cells. MT1-MMP is a potent membrane proteinase employed by aggressive cancer cells. In our previous study, we reported that MT1-MMP was preferentially located at membrane protrusions called invadopodia, where...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667784/ https://www.ncbi.nlm.nih.gov/pubmed/23737743 http://dx.doi.org/10.1371/journal.pcbi.1003086 |