DSG3 Facilitates Cancer Cell Growth and Invasion through the DSG3-Plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP Signaling Pathway

Desmoglein 3 (DSG3) is a component of the desmosome, which confers strong cell-cell adhesion. Previously, an oncogenic function of DSG3 has been found in head neck cancer (HNC). Here, we investigated how this molecule contributes to the malignant phenotype. Because DSG3 is associated with plakoglobi...

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Detalles Bibliográficos
Autores principales: Chen, Yin-Ju, Lee, Li-Yu, Chao, Yin-Ka, Chang, Joseph T., Lu, Ya-Ching, Li, Hsiao-Fang, Chiu, Ching-Chi, Li, Yi-Chen, Li, Yan-Liang, Chiou, Jeng-Fong, Cheng, Ann-Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667790/
https://www.ncbi.nlm.nih.gov/pubmed/23737966
http://dx.doi.org/10.1371/journal.pone.0064088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667790/
https://www.ncbi.nlm.nih.gov/pubmed/23737966
http://dx.doi.org/10.1371/journal.pone.0064088

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