An RNA Aptamer Provides a Novel Approach for the Induction of Apoptosis by Targeting the HPV16 E7 Oncoprotein

BACKGROUND: Human papillomavirus 16 (HPV16) is a high-risk DNA tumour virus, which is a major causative agent of cervical cancer. Cellular transformation is associated with deregulated expression of the E6 and E7 oncogenes. E7 has been shown to bind a number of cellular proteins, including the cell...

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Detalles Bibliográficos
Autores principales: Nicol, Clare, Cesur, Özlem, Forrest, Sophie, Belyaeva, Tamara A., Bunka, David H. J., Blair, G. Eric, Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667794/
https://www.ncbi.nlm.nih.gov/pubmed/23738000
http://dx.doi.org/10.1371/journal.pone.0064781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667794/
https://www.ncbi.nlm.nih.gov/pubmed/23738000
http://dx.doi.org/10.1371/journal.pone.0064781

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