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Testing the Utility of an Integrated Analysis of Copy Number and Transcriptomics Datasets for Inferring Gene Regulatory Relationships

Correlation patterns between matched copy number variation and gene expression data in cancer samples enable the inference of causal gene regulatory relationships by exploiting the natural randomization of such systems. The aim of this study was to test and verify experimentally the accuracy of a ca...

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Detalles Bibliográficos
Autores principales: Goh, Xin Yi, Newton, Richard, Wernisch, Lorenz, Fitzgerald, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667814/
https://www.ncbi.nlm.nih.gov/pubmed/23737949
http://dx.doi.org/10.1371/journal.pone.0063780