Active Suppression Induced by Repetitive Self-Epitopes Protects against EAE Development

BACKGROUND: Autoimmune diseases result from a breakdown in self-tolerance to autoantigens. Self-tolerance is induced and sustained by central and peripheral mechanisms intended to deviate harmful immune responses and to maintain homeostasis, where regulatory T cells play a crucial role. The use of s...

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Detalles Bibliográficos
Autores principales: Puentes, Fabiola, Dickhaut, Katharina, Hofstätter, Maria, Falk, Kirsten, Rötzschke, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667816/
https://www.ncbi.nlm.nih.gov/pubmed/23738007
http://dx.doi.org/10.1371/journal.pone.0064888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667816/
https://www.ncbi.nlm.nih.gov/pubmed/23738007
http://dx.doi.org/10.1371/journal.pone.0064888

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