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Reverse Engineering of Modified Genes by Bayesian Network Analysis Defines Molecular Determinants Critical to the Development of Glioblastoma

In this study we have identified key genes that are critical in development of astrocytic tumors. Meta-analysis of microarray studies which compared normal tissue to astrocytoma revealed a set of 646 differentially expressed genes in the majority of astrocytoma. Reverse engineering of these 646 gene...

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Detalles Bibliográficos
Autores principales: Kunkle, Brian W., Yoo, Changwon, Roy, Deodutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667850/
https://www.ncbi.nlm.nih.gov/pubmed/23737970
http://dx.doi.org/10.1371/journal.pone.0064140