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A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies

Benzothiazole derivatives are known for various biological activities, and their potency in cancer therapy has received considerable attention in recent years. YLT322, a novel synthesized benzothiazole derivative, exhibits potent anti-tumor activity via inducing apoptosis both in vitro and in vivo....

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Detalles Bibliográficos
Autores principales: Xuejiao, Song, Yong, Xia, Ningyu, Wang, Lidan, Zhang, Xuanhong, Shi, Youzhi, Xu, Tinghong, Ye, Yaojie, Shi, Yongxia, Zhu, Luoting, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667852/
https://www.ncbi.nlm.nih.gov/pubmed/23737957
http://dx.doi.org/10.1371/journal.pone.0063900