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Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment: A dangerous liaison

Tumor-infiltrating plasmacytoid dendritic cells (pDCs) have been associated with poor patient prognosis. We have recently uncovered the ability of pDCs to activate and expand a subset of tumor-infiltrating FOXP3(+) regulatory T cells that express inducible costimulator (ICOS), providing new insights...

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Detalles Bibliográficos
Autores principales: Conrad, Curdin, Gilliet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667894/
https://www.ncbi.nlm.nih.gov/pubmed/23762788
http://dx.doi.org/10.4161/onci.23887