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A Janus-faced role of the unfolded protein response in antitumor immunity

The unfolded protein response (UPR) has been established as a cell-intrinsic mechanism of survival for malignant cells facing microenvironmental stressors. Recent evidence indicates that the UPR also modulates antitumor immunity. Here, we discuss the bi-faced role of the UPR as it both promotes and...

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Detalles Bibliográficos
Autores principales: Mahadevan, Navin R., Rodvold, Jeffrey J., Zanetti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667895/
https://www.ncbi.nlm.nih.gov/pubmed/23762789
http://dx.doi.org/10.4161/onci.23901