Myeloid-derived suppressor cells as a novel target for the control of osteolytic bone disease

Myeloid-derived suppressor cells (MDSC) from mice bearing bone metastases differentiate into functional osteoclasts in vitro and in vivo, through a signaling pathway that relies on nitric oxide. In addition, MDSC-targeting drugs have been shown to robustly inhibit osteolysis. Thus, MDSC stand out as...

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Detalles Bibliográficos
Autores principales: Sawant, Anandi, Ponnazhagan, Selvarangan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667900/
https://www.ncbi.nlm.nih.gov/pubmed/23762794
http://dx.doi.org/10.4161/onci.24064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667900/
https://www.ncbi.nlm.nih.gov/pubmed/23762794
http://dx.doi.org/10.4161/onci.24064

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