Development of a robust cell-based high-throughput screening assay to identify targets of HIV-1 viral protein R dimerization

Targeting protein–protein interactions (PPI) is an emerging field in drug discovery. Dimerization and PPI are essential properties of human immunodeficiency virus (HIV)-1 proteins, their mediated functions, and virus biology. Additionally, dimerization is required for the functional interaction of H...

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Detalles Bibliográficos
Autores principales: Zych, Courtney, Domling, Alexander, Ayyavoo, Velpandi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668091/
https://www.ncbi.nlm.nih.gov/pubmed/23737660
http://dx.doi.org/10.2147/DDDT.S44139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668091/
https://www.ncbi.nlm.nih.gov/pubmed/23737660
http://dx.doi.org/10.2147/DDDT.S44139

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