Analysis of the potential effect of ponatinib on the QTc interval in patients with refractory hematological malignancies

PURPOSE: Cardiac dysfunction, particularly QT interval prolongation, has been observed with tyrosine kinase inhibitors approved to treat chronic myeloid leukemia. This study examines the effects of ponatinib on cardiac repolarization in patients with refractory hematological malignancies enrolled in...

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Detalles Bibliográficos
Autores principales: Sonnichsen, Daryl, Dorer, David J., Cortes, Jorge, Talpaz, Moshe, Deininger, Michael W., Shah, Neil P., Kantarjian, Hagop M., Bixby, Dale, Mauro, Michael J., Flinn, Ian W., Litwin, Jeffrey, Turner, Christopher D., Haluska, Frank G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668123/
https://www.ncbi.nlm.nih.gov/pubmed/23609479
http://dx.doi.org/10.1007/s00280-013-2160-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668123/
https://www.ncbi.nlm.nih.gov/pubmed/23609479
http://dx.doi.org/10.1007/s00280-013-2160-7

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