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Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs). Incorporating eQTL information hence has potential to increase power of genome-wide association studies (GWAS). In this paper, we...

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Detalles Bibliográficos
Autores principales: Li, Lin, Kabesch, Michael, Bouzigon, Emmanuelle, Demenais, Florence, Farrall, Martin, Moffatt, Miriam F., Lin, Xihong, Liang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668139/
https://www.ncbi.nlm.nih.gov/pubmed/23755072
http://dx.doi.org/10.3389/fgene.2013.00103