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In vivo and in silico analysis of PCNA ubiquitylation in the activation of the Post Replication Repair pathway in S. cerevisiae
BACKGROUND: The genome of living organisms is constantly exposed to several damaging agents that induce different types of DNA lesions, leading to cellular malfunctioning and onset of many diseases. To maintain genome stability, cells developed various repair and tolerance systems to counteract the...
Autores principales: | Amara, Flavio, Colombo, Riccardo, Cazzaniga, Paolo, Pescini, Dario, Csikász-Nagy, Attila, Falconi, Marco Muzi, Besozzi, Daniela, Plevani, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668150/ https://www.ncbi.nlm.nih.gov/pubmed/23514624 http://dx.doi.org/10.1186/1752-0509-7-24 |
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