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Effect of Normalization on Statistical and Biological Interpretation of Gene Expression Profiles

An under-appreciated aspect of the genetic analysis of gene expression is the impact of post-probe level normalization on biological inference. Here we contrast nine different methods for normalization of an Illumina bead-array gene expression profiling dataset consisting of peripheral blood samples...

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Detalles Bibliográficos
Autores principales:	Qin, Shaopu, Kim, Jinhee, Arafat, Dalia, Gibson, Greg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668151/ https://www.ncbi.nlm.nih.gov/pubmed/23755061 http://dx.doi.org/10.3389/fgene.2012.00160

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