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Homology modeling and virtual screening approaches to identify potent inhibitors of VEB-1 β-lactamase
BACKGROUND: bla(VEB-1) is an integron-located extended-spectrum β-lactamase gene initially detected in Escherichia coli and Pseudomonas aeruginosa strains from south-east Asia. Several recent studies have reported that VEB-1-positive strains are highly resistant to ceftazidime, cefotaxime and aztreo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668210/ https://www.ncbi.nlm.nih.gov/pubmed/23547944 http://dx.doi.org/10.1186/1742-4682-10-22 |