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Screening and identification of genetic loci involved in producing more/denser inclusion bodies in Escherichia coli

BACKGROUND: Many proteins and peptides have been used in therapeutic or industrial applications. They are often produced in microbial production hosts by fermentation. Robust protein production in the hosts and efficient downstream purification are two critical factors that could significantly reduc...

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Detalles Bibliográficos
Autores principales: Pandey, Neeraj, Sachan, Annapurna, Chen, Qi, Ruebling-Jass, Kristin, Bhalla, Ritu, Panguluri, Kiran Kumar, Rouviere, Pierre E, Cheng, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668246/
https://www.ncbi.nlm.nih.gov/pubmed/23638724
http://dx.doi.org/10.1186/1475-2859-12-43