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A Review of Targeted Therapies Evaluated by the Pediatric Preclinical Testing Program for Osteosarcoma
Osteosarcoma, the most common malignant bone tumor of childhood, is a high-grade primary bone sarcoma that occurs mostly in adolescence. Standard treatment consists of surgery in combination with multi-agent chemotherapy regimens. The development and approval of imatinib for Philadelphia chromosome-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668267/ https://www.ncbi.nlm.nih.gov/pubmed/23755370 http://dx.doi.org/10.3389/fonc.2013.00132 |