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Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

Individual cells from a genetically identical population exhibit substantial variation in gene expression. A significant part of this variation is due to noise in the process of transcription that is intrinsic to each gene, and is determined by factors such as the rate with which the promoter transi...

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Detalles Bibliográficos
Autores principales: Dadiani, Maya, van Dijk, David, Segal, Barak, Field, Yair, Ben-Artzi, Gil, Raveh-Sadka, Tali, Levo, Michal, Kaplow, Irene, Weinberger, Adina, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668364/
https://www.ncbi.nlm.nih.gov/pubmed/23403035
http://dx.doi.org/10.1101/gr.149096.112