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Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise
Individual cells from a genetically identical population exhibit substantial variation in gene expression. A significant part of this variation is due to noise in the process of transcription that is intrinsic to each gene, and is determined by factors such as the rate with which the promoter transi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668364/ https://www.ncbi.nlm.nih.gov/pubmed/23403035 http://dx.doi.org/10.1101/gr.149096.112 |