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A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing

Most mammalian genes produce multiple mRNA isoforms derived from alternative pre-mRNA splicing, with each alternative exon controlled by a complex network of regulatory factors. The identification of these regulators can be laborious and is usually carried out one factor at a time. We have developed...

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Detalles Bibliográficos
Autores principales: Zheng, Sika, Damoiseaux, Robert, Chen, Liang, Black, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668367/
https://www.ncbi.nlm.nih.gov/pubmed/23636947
http://dx.doi.org/10.1101/gr.147546.112