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Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancer

The past few years have witnessed something of a renaissance in the field of cancer immunotherapy, relating largely to the clinical advances that have been associated with the development of monoclonal antibodies targeting the immune inhibitory co-receptors CTLA-4 and PD-1 and to the pursuit of gene...

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Detalles Bibliográficos
Autores principales: Quezada, S A, Peggs, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668483/
https://www.ncbi.nlm.nih.gov/pubmed/23511566
http://dx.doi.org/10.1038/bjc.2013.117