Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site()

l-Rhamnose isomerase (l-RhI) catalyzes the reversible isomerization of l-rhamnose to l-rhamnulose. Previously determined X-ray structures of l-RhI showed a hydride-shift mechanism for the isomerization of substrates in a linear form, but the mechanism for opening of the sugar-ring is still unclear....

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Detalles Bibliográficos
Autores principales: Yoshida, Hiromi, Yoshihara, Akihide, Teraoka, Misa, Yamashita, Satoshi, Izumori, Ken, Kamitori, Shigehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668531/
https://www.ncbi.nlm.nih.gov/pubmed/23772372
http://dx.doi.org/10.1016/j.fob.2012.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668531/
https://www.ncbi.nlm.nih.gov/pubmed/23772372
http://dx.doi.org/10.1016/j.fob.2012.11.008

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