Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2()

EphA2 is activated through phosphorylation on serine 897 (S897) by Akt to promote cancer cell motility and invasion, independently of stimulation by ephrin, its ligand. Here we show that S897 phosphorylation of EphA2 strengthens the interaction between EphA2 and Ephexin4, a guanine nucleotide exchan...

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Detalles Bibliográficos
Autores principales: Kawai, Hiromu, Kobayashi, Masakazu, Hiramoto-Yamaki, Nao, Harada, Kohei, Negishi, Manabu, Katoh, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668535/
https://www.ncbi.nlm.nih.gov/pubmed/23772378
http://dx.doi.org/10.1016/j.fob.2013.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668535/
https://www.ncbi.nlm.nih.gov/pubmed/23772378
http://dx.doi.org/10.1016/j.fob.2013.01.002

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