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Further structural insights into the binding of complement factor H by complement regulator-acquiring surface protein 1 (CspA) of Borrelia burgdorferi

Borrelia burgdorferi has evolved many mechanisms of evading the different immune systems across its range of reservoir hosts, including the capture and presentation of host complement regulators factor H and factor H-like protein-1 (FHL-1). Acquisition is mediated by a family of complement regulator...

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Detalles Bibliográficos
Autores principales: Caesar, Joseph J. E., Wallich, Reinhard, Kraiczy, Peter, Zipfel, Peter F., Lea, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668580/
https://www.ncbi.nlm.nih.gov/pubmed/23722839
http://dx.doi.org/10.1107/S1744309113012748