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PTPL1 and PKCδ contribute to proapoptotic signalling in prostate cancer cells

PTPL1 is a non-receptor protein tyrosine phosphatase involved in apoptosis regulation, although controversial findings have been reported in different cancer types. We report here a proapoptotic role for PTPL1 in PC3 and LNCaP prostate cancer cells, as its absence induces apoptosis resistance upon t...

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Detalles Bibliográficos
Autores principales: Castilla, C, Chinchón, D, Medina, R, Torrubia, F J, Japón, M A, Sáez, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668626/
https://www.ncbi.nlm.nih.gov/pubmed/23559010
http://dx.doi.org/10.1038/cddis.2013.90