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PTPL1 and PKCδ contribute to proapoptotic signalling in prostate cancer cells
PTPL1 is a non-receptor protein tyrosine phosphatase involved in apoptosis regulation, although controversial findings have been reported in different cancer types. We report here a proapoptotic role for PTPL1 in PC3 and LNCaP prostate cancer cells, as its absence induces apoptosis resistance upon t...
Autores principales: | Castilla, C, Chinchón, D, Medina, R, Torrubia, F J, Japón, M A, Sáez, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668626/ https://www.ncbi.nlm.nih.gov/pubmed/23559010 http://dx.doi.org/10.1038/cddis.2013.90 |
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