Rare Variant Association Testing for Next-Generation Sequencing Data via Hierarchical Clustering

OBJECTIVES: It is thought that a proportion of the genetic susceptibility to complex diseases is due to low-frequency and rare variants. Next-generation sequencing in large populations facilitates the detection of rare variant associations to disease risk. In order to achieve adequate power to detec...

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Detalles Bibliográficos
Autores principales: Tachmazidou, Ioanna, Morris, Andrew, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668801/
https://www.ncbi.nlm.nih.gov/pubmed/23594494
http://dx.doi.org/10.1159/000346022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668801/
https://www.ncbi.nlm.nih.gov/pubmed/23594494
http://dx.doi.org/10.1159/000346022

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