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Rare Variant Association Testing for Next-Generation Sequencing Data via Hierarchical Clustering

OBJECTIVES: It is thought that a proportion of the genetic susceptibility to complex diseases is due to low-frequency and rare variants. Next-generation sequencing in large populations facilitates the detection of rare variant associations to disease risk. In order to achieve adequate power to detec...

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Detalles Bibliográficos
Autores principales:	Tachmazidou, Ioanna, Morris, Andrew, Zeggini, Eleftheria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2013
Materias:	Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668801/ https://www.ncbi.nlm.nih.gov/pubmed/23594494 http://dx.doi.org/10.1159/000346022

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