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Multidrug resistance protein MdtM adds to the repertoire of antiporters involved in alkaline pH homeostasis in Escherichia coli

BACKGROUND: In neutralophilic bacteria, monovalent metal cation/H(+) antiporters play a key role in pH homeostasis. In Escherichia coli, only four antiporters (NhaA, NhaB, MdfA and ChaA) are identified to function in maintenance of a stable cytoplasmic pH under conditions of alkaline stress. We hypo...

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Detalles Bibliográficos
Autores principales: Holdsworth, Scarlett R, Law, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668916/
https://www.ncbi.nlm.nih.gov/pubmed/23701827
http://dx.doi.org/10.1186/1471-2180-13-113