Impact of pyrrolidine-bispyrrole DNA minor groove binding agents and chirality on global proteomic profile in Escherichia Coli

BACKGROUND: There is great interest in the design of small molecules that selectively target minor grooves of duplex DNA for controlling specific gene expression implicated in a disease. The design of chiral small molecules for rational drug design has attracted increasing attention due to the chira...

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Detalles Bibliográficos
Autores principales: Yang, Ya-ting, Lin, Chun-Yu, Jeng, Jingyueh, Ong, Chi-Wi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669006/
https://www.ncbi.nlm.nih.gov/pubmed/23702249
http://dx.doi.org/10.1186/1477-5956-11-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669006/
https://www.ncbi.nlm.nih.gov/pubmed/23702249
http://dx.doi.org/10.1186/1477-5956-11-23

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