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Estimation of Low Quantity Genes: A Hierarchical Model for Analyzing Censored Quantitative Real-Time PCR Data

Analysis of gene quantities measured by quantitative real-time PCR (qPCR) can be complicated by observations that are below the limit of quantification (LOQ) of the assay. A hierarchical model estimated using MCMC methods was developed to analyze qPCR data of genes with observations that fall below...

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Detalles Bibliográficos
Autores principales: Boyer, Tim C., Hanson, Tim, Singer, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669010/
https://www.ncbi.nlm.nih.gov/pubmed/23741414
http://dx.doi.org/10.1371/journal.pone.0064900