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Successful Isolation of Infectious and High Titer Human Monocyte-Derived HIV-1 from Two Subjects with Discontinued Therapy

BACKGROUND: HIV-1 DNA in blood monocytes is considered a viral source of various HIV-1 infected tissue macrophages, which is also known as “Trojan horse” hypothesis. However, whether these DNA can produce virions has been an open question for years, due to the inability of isolating high titer and i...

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Detalles Bibliográficos
Autores principales: Wang, Tong, Xu, Younong, Zhu, Haiying, Andrus, Thomas, Ivanov, Sergei B., Pan, Charlotte, Dolores, Jazel, Dann, Gregory C., Zhou, Michael, Forte, Dominic, Yang, Zihuan, Holte, Sarah, Corey, Lawrence, Zhu, Tuofu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669022/
https://www.ncbi.nlm.nih.gov/pubmed/23741458
http://dx.doi.org/10.1371/journal.pone.0065071