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Expression of the Growth Factor Progranulin in Endothelial Cells Influences Growth and Development of Blood Vessels: A Novel Mouse Model

Progranulin is a secreted glycoprotein that regulates cell proliferation, migration and survival. It has roles in development, tumorigenesis, wound healing, neurodegeneration and inflammation. Endothelia in tumors, wounds and placenta express elevated levels of progranulin. In culture, progranulin a...

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Detalles Bibliográficos
Autores principales: Toh, Huishi, Cao, Mingju, Daniels, Eugene, Bateman, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669103/
https://www.ncbi.nlm.nih.gov/pubmed/23741441
http://dx.doi.org/10.1371/journal.pone.0064989