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Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study

BACKGROUND: High-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels are influenced by both genes and the environment. Genome-wide association studies (GWAS) have identified ~100 common genetic variants associated with HDL-C, LDL-C, and/...

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Detalles Bibliográficos
Autores principales: Taylor, Kira C, Carty, Cara L, Dumitrescu, Logan, Bůžková, Petra, Cole, Shelley A, Hindorff, Lucia, Schumacher, Fred R, Wilkens, Lynne R, Shohet, Ralph V, Quibrera, P Miguel, Johnson, Karen C, Henderson, Brian E, Haessler, Jeff, Franceschini, Nora, Eaton, Charles B, Duggan, David J, Cochran, Barbara, Cheng, Iona, Carlson, Chris S, Brown-Gentry, Kristin, Anderson, Garnet, Ambite, Jose Luis, Haiman, Christopher, Le Marchand, Loïc, Kooperberg, Charles, Crawford, Dana C, Buyske, Steven, North, Kari E, Fornage, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669109/
https://www.ncbi.nlm.nih.gov/pubmed/23634756
http://dx.doi.org/10.1186/1471-2156-14-33