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Bridging epigenetics and metabolism: Role of non-essential amino acids

Recent research suggests that chromatin-modifying enzymes are metabolic sensors regulating gene expression. Epigenetics is linked to metabolomics in response to the cellular microenvironment. Specific metabolites involved in this sensing mechanism include S-adenosylmethionine, acetyl-CoA, alphaketog...

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Detalles Bibliográficos
Autores principales: Phang, James M., Liu, Wei, Hancock, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669115/
https://www.ncbi.nlm.nih.gov/pubmed/23422013
http://dx.doi.org/10.4161/epi.24042