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An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

The proper identification of differentially methylated CpGs is central in most epigenetic studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA methylation; nevertheless, the design of an appropriate analysis pipeline faces severe challenges due to the convolution of biol...

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Detalles Bibliográficos
Autores principales: Marabita, Francesco, Almgren, Malin, Lindholm, Maléne E., Ruhrmann, Sabrina, Fagerström-Billai, Fredrik, Jagodic, Maja, Sundberg, Carl J., Ekström, Tomas J., Teschendorff, Andrew E., Tegnér, Jesper, Gomez-Cabrero, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669124/
https://www.ncbi.nlm.nih.gov/pubmed/23422812
http://dx.doi.org/10.4161/epi.24008