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Conditional Inactivation of p53 in Mouse Ovarian Surface Epithelium Does Not Alter MIS Driven Smad2-Dominant Negative Epithelium-Lined Inclusion Cysts or Teratomas

Epithelial ovarian cancer is the most lethal gynecological malignancy among US women. The etiology of this disease, although poorly understood, may involve the ovarian surface epithelium or the epithelium of the fallopian tube fimbriae as the progenitor cell. Disruptions in the transforming growth f...

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Detalles Bibliográficos
Autores principales: Quartuccio, Suzanne M., Lantvit, Daniel D., Bosland, Maarten C., Burdette, Joanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669126/
https://www.ncbi.nlm.nih.gov/pubmed/23741457
http://dx.doi.org/10.1371/journal.pone.0065067