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1,25-Dihydroxyvitamin D(3) Inhibits Podocyte uPAR Expression and Reduces Proteinuria

BACKGROUND: Accumulating studies have demonstrated that 1,25-Dihydroxyvitamin D(3) (1,25(OH)2D3) reduces proteinuria and protects podocytes from injury. Recently, urokinase receptor (uPAR) and its soluble form have been shown to cause podocyte injury and focal segmental glomerulosclerosis (FSGS). He...

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Detalles Bibliográficos
Autores principales: Ma, Jianchao, Zhang, Bin, Liu, Shuangxin, Xie, Shaoting, Yang, Yun, Ma, Juan, Deng, Yujun, Wang, Wenjian, Xu, Lixia, Li, Ruizhao, Zhang, Li, Yu, Chunping, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669128/
https://www.ncbi.nlm.nih.gov/pubmed/23741418
http://dx.doi.org/10.1371/journal.pone.0064912